Androgen ester

Multi tool use
Multi tool use




Testosterone undecanoate, an ester of testosterone and one of the most widely used androgen esters.


An androgen or anabolic steroid ester is an ester of an androgen/anabolic steroid (AAS) such as the natural testosterone or dihydrotestosterone (DHT) or the synthetic nandrolone (19-nortestosterone). Esterification renders AAS into metabolism-resistant prohormones of themselves, improving oral bioavailability, increasing lipophilicity, and extending the elimination half-life (which necessitates less frequent administration). In addition, with intramuscular injection, AAS esters are absorbed more slowly into the body, further improving the elimination half-life. Aside from differences in pharmacokinetics (e.g., duration), these esters essentially have the same effects as the parent drugs.[1] They are used in androgen replacement therapy (ART), among other indications. Examples of androgen esters include testosterone esters such as testosterone cypionate, testosterone enanthate, testosterone propionate, and testosterone undecanoate and nandrolone esters such as nandrolone decanoate and nandrolone phenylpropionate.














































































  • v

  • t

  • e

Structural properties of major testosterone esters

AndrogenStructureEster
Rel. MWb
Rel. Tc		Durationd
PositionMoietyTypeLengthaRankGroup
TestosteroneTestosteron.svg––––1.001.006Short
Testosterone propionateTestosterone propionate.svgC17βPropanoic acidStraight-chain fatty acid31.190.845Short
Testosterone cypionateTestosterone cypionate.svgC17βCyclopentylpropanoic acidAromatic fatty acid– (~6)1.430.704Moderate
Testosterone enanthateTestosterone enanthate.svgC17βHeptanoic acidStraight-chain fatty acid71.390.723Moderate
Testosterone undecanoateTestosterone undecanoate.svgC17βUndecanoic acidStraight-chain fatty acid111.580.632Long

Testosterone buciclatee		Testosteronebuciclate structure.pngC17β
Bucyclic acidf		Aromatic carboxylic acid– (~9)1.580.631Long

Footnotes: a = Length of ester in carbon atoms for straight-chain fatty acids or approximate length of ester in carbon atoms for aromatic fatty acids. b = Relative molecular weight. c = Relative testosterone content by weight (i.e., relative androgenic potency). d = Duration by intramuscular or subcutaneous injection. e = Never marketed. f = Bucyclic acid = trans-4-Butylcyclohexane-1-carboxylic acid. Sources: See individual articles.






















































































  • v

  • t

  • e

Structural properties of major anabolic steroid esters

Anabolic steroidStructureEster
Rel. MWb
Rel. AASc		Durationd
PositionMoietyTypeLengtha
Boldenone undecylenateBoldenone undecylenate.svgC17βUndecylenic acidStraight-chain fatty acid111.580.63Long
Drostanolone propionateDrostanolone propionate.svgC17βPropanoic acidStraight-chain fatty acid31.180.84Short
Metenolone acetateMetenolone acetate.svgC17βEthanoic acidStraight-chain fatty acid21.140.88Short
Metenolone enanthateMetenolone enanthate.pngC17βHeptanoic acidStraight-chain fatty acid71.370.73Long
Nandrolone decanoateNandrolone decanoate.svgC17βDecanoic acidStraight-chain fatty acid101.560.64Long
Nandrolone phenylpropionateNandrolone phenylpropionate.svgC17βPhenylpropanoic acidAromatic fatty acid– (~6–7)1.480.67Long
Trenbolone acetateTrenbolone acetate.svgC17βEthanoic acidStraight-chain fatty acid21.160.87Short

Trenbolone enanthatee		Trenbolone enanthate.svgC17βHeptanoic acidStraight-chain fatty acid71.410.71Long

Footnotes: a = Length of ester in carbon atoms for straight-chain fatty acids or approximate length of ester in carbon atoms for aromatic fatty acids. b = Relative molecular weight compared to unesterified parent steroid. c = Relative anabolic steroid content by weight (i.e., relative androgenic potency) compared to unesterified parent steroid. d = Duration by intramuscular or subcutaneous injection. e = Never marketed. Sources: See individual articles.


See also


  • List of androgen esters

  • List of androgens/anabolic steroids

  • Steroid ester

  • Estrogen ester

  • Progestogen ester


References




  1. ^ Richard Lawrence Miller (2002). The Encyclopedia of Addictive Drugs. Greenwood Publishing Group. pp. 416–. ISBN 978-0-313-31807-8..mw-parser-output cite.citationfont-style:inherit.mw-parser-output .citation qquotes:"""""""'""'".mw-parser-output .citation .cs1-lock-free abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-subscription abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registrationcolor:#555.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration spanborder-bottom:1px dotted;cursor:help.mw-parser-output .cs1-ws-icon abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center.mw-parser-output code.cs1-codecolor:inherit;background:inherit;border:inherit;padding:inherit.mw-parser-output .cs1-hidden-errordisplay:none;font-size:100%.mw-parser-output .cs1-visible-errorfont-size:100%.mw-parser-output .cs1-maintdisplay:none;color:#33aa33;margin-left:0.3em.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-formatfont-size:95%.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-leftpadding-left:0.2em.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-rightpadding-right:0.2em



Further reading



  • Vermeulen A (1975). "Longacting steroid preparations". Acta Clin Belg. 30 (1): 48–55. doi:10.1080/17843286.1975.11716973. PMID 1231448.










sirPkUAf,wUsWbQH05WDDKJQv1U2YacXV9,dvWZzW9dFk4Sncyf4alemAxHbs6 q0C,OPI414j
-
uYpTciDtyps43Q7WLcQwZ,xvVMwHEwRNT1HT3RalfBs,dxH L0MpntBDIWRb,Ao0,sM

Popular posts from this blog

How to check contact read email or not when send email to Individual?

Image
Clash Royale CLAN TAG #URR8PPP up vote 1 down vote favorite I'm using WordPress 4.9.8, CiviCRM to 5.5.1, I usually send email to contact by Search> Find contacts View contact details Action> Send email Send email ok, Contact received mail ok like picture But status only Email sent though contact read email or not. So, can CiviCRM can change status to Email read when contact read email? wordpress email share | improve this question asked Sep 26 at 0:12 ToanLuong 49 9 add a comment  |  up vote 1 down vote favorite I'm using WordPress 4.9.8, CiviCRM to 5.5.1, I usually send email to contact by Search> Find contacts View contact details Action> Send email Send email ok, Contact received mail ok like picture But status only Email sent though contact read email or not. So, can CiviCRM can change status to Email read when contact read email? wordpress email share | improve this questi...
Read more

How many registers does an x86_64 CPU actually have?

Image
Clash Royale CLAN TAG #URR8PPP up vote 2 down vote favorite I am currently learning reverse engineering and am studying the flags register. I had in my mind that rflags was just another name for one of the 16 general purpose registers, for example rax or rbx . But it looks like rflags is actually an additional register. So that makes 17 registers in total... how many more could there be? I have spent at least an hour on this and found numerous different answers. The best answer so far is this, which says that there are 40 registers in total. 16 General Purpose Registers 2 Status Registers 6 Code Segment Registers 16 SSE Registers 8 FPU/MMX Registers But if I add that up, I get 48. Could anybody provide an official answer on how many registers an x86_64 CPU has (e.g. an Intel i7). Additionally, I have seen references to 'hardware' and 'architectural' registers. What are those registers and how many are there? register x86-64 share | improve this...
Read more

Displaying single band from multi-band raster using QGIS

Image
Clash Royale CLAN TAG #URR8PPP 1 How can I extract a single band from multi-band raster in QGIS? I have an remote sensed image which has 6 bands (including NDVI band), I want to display each band separately, but have no idea how to do. I have seen some questions similar here but none worked for me. The original image (has 6 bands) is: I want to display the band 6 which should be like this: But I tried gdal_translate, and couldn't get the correct result. What I have got is: qgis raster multi-band share | improve this question edited Mar 5 at 0:53 Summer asked Mar 4 at 6:42 Summer Summer 23 6 Is this any help gis.stackexchange.com/questions/220658/… ? if not gis.stackexchange.com/questions/62133/… might help. – Michael Stimson Mar 4 at 6:46 Thanks for answering but when I used gdal_translate, qgis showed that 'Error 4: Kayena.tif: No such file or directory". Would you know how to fi...
Read more