How can a school be getting an epidemic of whooping cough if most of the students are vaccinated?
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Apparently a private school is experiencing an outbreak of whooping cough. However, the article said that only 18 of the students in the school (out of 1500 or so) were unvaccinated, yet already 30 have the disease. Presumably some of the infected students were vaccinated. How can this be?
vaccination whooping-cough epidemic
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Apparently a private school is experiencing an outbreak of whooping cough. However, the article said that only 18 of the students in the school (out of 1500 or so) were unvaccinated, yet already 30 have the disease. Presumably some of the infected students were vaccinated. How can this be?
vaccination whooping-cough epidemic
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– De Novo
Feb 27 at 21:54
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Apparently a private school is experiencing an outbreak of whooping cough. However, the article said that only 18 of the students in the school (out of 1500 or so) were unvaccinated, yet already 30 have the disease. Presumably some of the infected students were vaccinated. How can this be?
vaccination whooping-cough epidemic
Apparently a private school is experiencing an outbreak of whooping cough. However, the article said that only 18 of the students in the school (out of 1500 or so) were unvaccinated, yet already 30 have the disease. Presumably some of the infected students were vaccinated. How can this be?
vaccination whooping-cough epidemic
vaccination whooping-cough epidemic
asked Feb 27 at 19:20
Tyler DurdenTyler Durden
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– De Novo
Feb 27 at 21:54
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– De Novo
Feb 27 at 21:54
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– De Novo
Feb 27 at 21:54
related
– De Novo
Feb 27 at 21:54
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1 Answer
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Per the CDC:
A: Pertussis vaccines are effective, but not perfect. They typically
offer good levels of protection within the first 2 years after getting
the vaccine, but then protection decreases over time. Public health
experts call this ‘waning immunity.’ Similarly, natural infection may
also only protect you for a few years.
In general, DTaP vaccines are 80% to 90% effective. Among kids who get
all 5 doses of DTaP on schedule, effectiveness is very high within the
year following the 5th dose – at least 9 out of 10 kids are fully
protected. There is a modest decrease in effectiveness in each
following year. About 7 out of 10 kids are fully protected 5 years
after getting their last dose of DTaP and the other 3 out of 10 kids
are partially protected – protecting against serious disease.
CDC’s current estimate is that in the first year after getting
vaccinated with Tdap, it protects about 7 out of 10 people who receive
it. There is a decrease in effectiveness in each following year. About
3 or 4 out of 10 people are fully protected 4 years after getting
Tdap.
Keeping up-to-date with recommended pertussis vaccines is the best way
to protect you and your loved ones.
Given the size of the school and the effectiveness of the vaccine, it appears that ~30 infected kids is within what's expected.
2
Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.
– De Novo
Feb 27 at 21:57
@DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.
– ShadowRanger
Feb 28 at 0:25
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protected by Carey Gregory♦ Feb 28 at 15:15
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Because it has attracted low-quality or spam answers that had to be removed, posting an answer now requires 10 reputation on this site (the association bonus does not count).
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1 Answer
1
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1 Answer
1
active
oldest
votes
active
oldest
votes
active
oldest
votes
Per the CDC:
A: Pertussis vaccines are effective, but not perfect. They typically
offer good levels of protection within the first 2 years after getting
the vaccine, but then protection decreases over time. Public health
experts call this ‘waning immunity.’ Similarly, natural infection may
also only protect you for a few years.
In general, DTaP vaccines are 80% to 90% effective. Among kids who get
all 5 doses of DTaP on schedule, effectiveness is very high within the
year following the 5th dose – at least 9 out of 10 kids are fully
protected. There is a modest decrease in effectiveness in each
following year. About 7 out of 10 kids are fully protected 5 years
after getting their last dose of DTaP and the other 3 out of 10 kids
are partially protected – protecting against serious disease.
CDC’s current estimate is that in the first year after getting
vaccinated with Tdap, it protects about 7 out of 10 people who receive
it. There is a decrease in effectiveness in each following year. About
3 or 4 out of 10 people are fully protected 4 years after getting
Tdap.
Keeping up-to-date with recommended pertussis vaccines is the best way
to protect you and your loved ones.
Given the size of the school and the effectiveness of the vaccine, it appears that ~30 infected kids is within what's expected.
2
Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.
– De Novo
Feb 27 at 21:57
@DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.
– ShadowRanger
Feb 28 at 0:25
add a comment |
Per the CDC:
A: Pertussis vaccines are effective, but not perfect. They typically
offer good levels of protection within the first 2 years after getting
the vaccine, but then protection decreases over time. Public health
experts call this ‘waning immunity.’ Similarly, natural infection may
also only protect you for a few years.
In general, DTaP vaccines are 80% to 90% effective. Among kids who get
all 5 doses of DTaP on schedule, effectiveness is very high within the
year following the 5th dose – at least 9 out of 10 kids are fully
protected. There is a modest decrease in effectiveness in each
following year. About 7 out of 10 kids are fully protected 5 years
after getting their last dose of DTaP and the other 3 out of 10 kids
are partially protected – protecting against serious disease.
CDC’s current estimate is that in the first year after getting
vaccinated with Tdap, it protects about 7 out of 10 people who receive
it. There is a decrease in effectiveness in each following year. About
3 or 4 out of 10 people are fully protected 4 years after getting
Tdap.
Keeping up-to-date with recommended pertussis vaccines is the best way
to protect you and your loved ones.
Given the size of the school and the effectiveness of the vaccine, it appears that ~30 infected kids is within what's expected.
2
Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.
– De Novo
Feb 27 at 21:57
@DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.
– ShadowRanger
Feb 28 at 0:25
add a comment |
Per the CDC:
A: Pertussis vaccines are effective, but not perfect. They typically
offer good levels of protection within the first 2 years after getting
the vaccine, but then protection decreases over time. Public health
experts call this ‘waning immunity.’ Similarly, natural infection may
also only protect you for a few years.
In general, DTaP vaccines are 80% to 90% effective. Among kids who get
all 5 doses of DTaP on schedule, effectiveness is very high within the
year following the 5th dose – at least 9 out of 10 kids are fully
protected. There is a modest decrease in effectiveness in each
following year. About 7 out of 10 kids are fully protected 5 years
after getting their last dose of DTaP and the other 3 out of 10 kids
are partially protected – protecting against serious disease.
CDC’s current estimate is that in the first year after getting
vaccinated with Tdap, it protects about 7 out of 10 people who receive
it. There is a decrease in effectiveness in each following year. About
3 or 4 out of 10 people are fully protected 4 years after getting
Tdap.
Keeping up-to-date with recommended pertussis vaccines is the best way
to protect you and your loved ones.
Given the size of the school and the effectiveness of the vaccine, it appears that ~30 infected kids is within what's expected.
Per the CDC:
A: Pertussis vaccines are effective, but not perfect. They typically
offer good levels of protection within the first 2 years after getting
the vaccine, but then protection decreases over time. Public health
experts call this ‘waning immunity.’ Similarly, natural infection may
also only protect you for a few years.
In general, DTaP vaccines are 80% to 90% effective. Among kids who get
all 5 doses of DTaP on schedule, effectiveness is very high within the
year following the 5th dose – at least 9 out of 10 kids are fully
protected. There is a modest decrease in effectiveness in each
following year. About 7 out of 10 kids are fully protected 5 years
after getting their last dose of DTaP and the other 3 out of 10 kids
are partially protected – protecting against serious disease.
CDC’s current estimate is that in the first year after getting
vaccinated with Tdap, it protects about 7 out of 10 people who receive
it. There is a decrease in effectiveness in each following year. About
3 or 4 out of 10 people are fully protected 4 years after getting
Tdap.
Keeping up-to-date with recommended pertussis vaccines is the best way
to protect you and your loved ones.
Given the size of the school and the effectiveness of the vaccine, it appears that ~30 infected kids is within what's expected.
answered Feb 27 at 20:06
ventsyvventsyv
2212
2212
2
Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.
– De Novo
Feb 27 at 21:57
@DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.
– ShadowRanger
Feb 28 at 0:25
add a comment |
2
Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.
– De Novo
Feb 27 at 21:57
@DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.
– ShadowRanger
Feb 28 at 0:25
2
2
Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.
– De Novo
Feb 27 at 21:57
Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.
– De Novo
Feb 27 at 21:57
@DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.
– ShadowRanger
Feb 28 at 0:25
@DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.
– ShadowRanger
Feb 28 at 0:25
add a comment |
protected by Carey Gregory♦ Feb 28 at 15:15
Thank you for your interest in this question.
Because it has attracted low-quality or spam answers that had to be removed, posting an answer now requires 10 reputation on this site (the association bonus does not count).
Would you like to answer one of these unanswered questions instead?
3
related
– De Novo
Feb 27 at 21:54